Safety and efficacy of subcutaneous adrenaline as a treatment for anaphylactic reactions to polyvalent antivenom.

نویسندگان

  • S A Kularatne
  • I B Gawarammana
  • P V Kumarasiri
  • N Senanayake
  • W P Dissanayake
  • H Ariyasena
چکیده

3. Fadilah SA, Sahrir S, Raymond AA, Cheong SK, Aziz JA, et al. Quantitation of T lymphocyte subsets helps to distinguish dengue hemorrhagic fever from classic dengue fever during the acute febrile stage. Southeast Asian Journal of Tropical Medicine and Public Health 1999; 30: 710–7. 4. Bardill B, Mengis C, Tschopp M, Wuillemin WA, Severe lgA-mediated autoimmune haemolytic anaemia in a 48yr-old woman. European Journal of Haematology 2003; 70: 60–3.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Low dose subcutaneous adrenaline to prevent acute adverse reactions to antivenom serum in people bitten by snakes: randomised, placebo controlled trial.

OBJECTIVE To assess the efficacy and safety of low dose adrenaline injected subcutaneously to prevent acute adverse reactions to polyspecific antivenom serum in patients admitted to hospital after snake bite. DESIGN Prospective, double blind, randomised, placebo controlled trial. SETTING District general hospital in Sri Lanka. SUBJECTS 105 patients with signs of envenomation after snake b...

متن کامل

Low-Dose Adrenaline, Promethazine, and Hydrocortisone in the Prevention of Acute Adverse Reactions to Antivenom following Snakebite: A Randomised, Double-Blind, Placebo-Controlled Trial

BACKGROUND Envenoming from snakebites is most effectively treated by antivenom. However, the antivenom available in South Asian countries commonly causes acute allergic reactions, anaphylactic reactions being particularly serious. We investigated whether adrenaline, promethazine, and hydrocortisone prevent such reactions in secondary referral hospitals in Sri Lanka by conducting a randomised, d...

متن کامل

Clinical safety of a polyvalent F(ab')2 equine antivenom in 223 African snake envenomations: a field trial in Cameroon. VAO (Venin Afrique de l'Ouest) Investigators.

A large-scale clinical trials was conducted, according to World Health Organization Good Clinical Practice guidelines, in 7 centres in north Cameroon to determine the safety and efficacy of a polyvalent antivenom composed of purified F(ab')2. This study included 223 patients presenting clinically with obvious snake bite, predominantly due to Echis ocellatus (viper), the most abundant species in...

متن کامل

Inhibition of Nephrotoxic Activity of Mesobuthus Eupeus Scorpion Venom by Commercial Polyvalent Antivenom in Rabbits

Background: Immunotherapy is the only specific treatment for scorpion envenomation. In the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (BUN and creatinine) induced by Mesobuthus eupeus (Me) scorpion venom was investigated in anesthetized rabbits. Methods: Twenty four rabbits were randomized into four gro...

متن کامل

Sequential randomised and double blind trial of promethazine prophylaxis against early anaphylactic reactions to antivenom for bothrops snake bites.

OBJECTIVE To investigate the efficacy of the H1 antihistamine promethazine against early anaphylactic reactions to antivenom. DESIGN Sequential randomised, double blind, placebo controlled trial. SETTING Public hospital in a venom research institute, São Paulo, Brazil. PARTICIPANTS 101 patients requiring antivenom treatment after being bitten by bothrops snakes. INTERVENTION Intramuscul...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Ceylon medical journal

دوره 48 4  شماره 

صفحات  -

تاریخ انتشار 2003